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BustedS13 · 08-12-2011, 10:28 AM

'Amazing' therapy wipes out leukemia in study - Health - Cancer - msnbc.com

Quote:

NEW YORK — Scientists are reporting the first clear success with a new approach for treating leukemia — turning the patients' own blood cells into assassins that hunt and destroy their cancer cells.
They've only done it in three patients so far, but the results were striking: Two appear cancer-free up to a year after treatment, and the third patient is improved but still has some cancer. Scientists are already preparing to try the same gene therapy technique for other kinds of cancer.
"It worked great. We were surprised it worked as well as it did," said Dr. Carl June, a gene therapy expert at the University of Pennsylvania. "We're just a year out now. We need to find out how long these remissions last."
He led the study, published Wednesday by two journals, New England Journal of Medicine and Science Translational Medicine.
It involved three men with very advanced cases of chronic lymphocytic leukemia, or CLL. The only hope for a cure now is bone marrow or stem cell transplants, which don't always work and carry a high risk of death.
Scientists have been working for years to find ways to boost the immune system's ability to fight cancer. Earlier attempts at genetically modifying bloodstream soldiers called T-cells have had limited success; the modified cells didn't reproduce well and quickly disappeared.
June and his colleagues made changes to the technique, using a novel carrier to deliver the new genes into the T-cells and a signaling mechanism telling the cells to kill and multiply.
That resulted in armies of "serial killer" cells that targeted cancer cells, destroyed them, and went on to kill new cancer as it emerged. It was known that T-cells attack viruses that way, but this is the first time it's been done against cancer, June said.

they haven't "cured cancer", but this is still amazing. hopefully they'll have things figured out by the time i'm diagnosed with cancer.

ronmcdon · 08-12-2011, 10:57 AM

Idk it could be possible that it's a cure.
Like the article mentioned, the key is long term results & a larger patient sample size.
At the very least, it's a much safer (and prob more affordable) alternative to stem cell transplants.

Great news.

axiomatik · 08-12-2011, 11:18 AM

Heard about it on the radio on my way home yesterday. Pretty exciting results. This will be the future of fighting cancer - manipulating the bodies own defenses to weed out the cancer. People who dream of building nanobots that will swim around your body and do this are doing just that - dreaming. Genetic manipulation is much easier and doesn't require reinventing the wheel.

ravinaziankid · 08-12-2011, 12:14 PM

I wonder if they could use something like this to prevent people from having cancer or making a cancer that hasn't been detected yet to be fought off. It could be like how people get the flu shots.

slowvia · 08-12-2011, 07:13 PM

Im pretty excited to hear about this considering Im a Leukemia surviver. Just wish they would have had this 4 years ago!

D.Bo · 08-12-2011, 07:40 PM

zombie outbreak?

tqstarburst · 08-12-2011, 08:09 PM

Woo, thank god. One step at a time.

BustedS13 · 08-13-2011, 09:40 AM

Quote:

Originally Posted by tqstarburst

Woo, thank god. One step at a time.

yes, thank god for creating cancer for scientists to have a fun project.

drift freaq · 08-13-2011, 11:10 AM

This is great news. I hope they find it works with other forms of Cancer I know someone who could benefit big time from the this treatment.

theicecreamdan · 08-13-2011, 11:17 AM

Quote:

Originally Posted by BustedS13

yes, thank god for creating cancer for scientists to have a fun project.

The lord works in mysterious ways.

*fliprayzin240sx* · 08-13-2011, 02:28 PM

Quote:

Originally Posted by D.Bo

zombie outbreak?

T-Cell, T-Virus, coincident that they're similar in naming?

DoobieS13 · 08-13-2011, 02:40 PM

Quote:

Originally Posted by D.Bo

zombie outbreak?

08-12-2011, 11:18 AM	#3
axiomatik Post Whore! Join Date: Dec 2003 Location: ATL Posts: 4,697 Trader Rating: (0) Feedback Score: 0 reviews	Heard about it on the radio on my way home yesterday. Pretty exciting results. This will be the future of fighting cancer - manipulating the bodies own defenses to weed out the cancer. People who dream of building nanobots that will swim around your body and do this are doing just that - dreaming. Genetic manipulation is much easier and doesn't require reinventing the wheel. __________________

08-13-2011, 11:10 AM	#9
drift freaq R.I.P. Aya, always love Join Date: Nov 2001 Location: Los Feliz/Hollywood Posts: 18,558 Trader Rating: (215) Rides Gallery: drift freaq Feedback Score: 215 reviews	This is great news. I hope they find it works with other forms of Cancer I know someone who could benefit big time from the this treatment. __________________ "Having a lot of tracks on a song is like putting stickers on a car to get more horsepower" New Video https://www.youtube.com/watch?v=uebV1OnbRsw Buy my mounts! http://zilvia.net/f/sale-items/51531...ns-mounts.html http://zilvia.net/f/tech-talk/317539...e-mouts-6.html

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08-12-2011, 10:57 AM	#2
ronmcdon Post Whore! Join Date: Sep 2005 Location: beverly hills Age: 86 Posts: 4,254 Trader Rating: (6) Feedback Score: 6 reviews	Idk it could be possible that it's a cure. Like the article mentioned, the key is long term results & a larger patient sample size. At the very least, it's a much safer (and prob more affordable) alternative to stem cell transplants. Great news.

08-12-2011, 12:14 PM	#4
ravinaziankid Zilvia Junkie Join Date: Dec 2007 Location: NYC Age: 38 Posts: 394 Trader Rating: (0) Feedback Score: 0 reviews	I wonder if they could use something like this to prevent people from having cancer or making a cancer that hasn't been detected yet to be fought off. It could be like how people get the flu shots.

08-12-2011, 07:13 PM	#5
slowvia Zilvia Junkie Join Date: Jun 2008 Location: OR Posts: 381 Trader Rating: (3) Feedback Score: 3 reviews	Im pretty excited to hear about this considering Im a Leukemia surviver. Just wish they would have had this 4 years ago!

08-12-2011, 07:40 PM	#6
D.Bo Zilvia Member Join Date: Mar 2007 Location: New Orleans Age: 32 Posts: 283 Trader Rating: (0) Feedback Score: 0 reviews	zombie outbreak?

08-12-2011, 08:09 PM	#7
tqstarburst Zilvia FREAK! Join Date: Mar 2010 Location: Texas Age: 29 Posts: 1,314 Trader Rating: (2) Feedback Score: 2 reviews	Woo, thank god. One step at a time.